Test Bank For Physiology of Behavior 11th Edition by Carlson

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Test Bank For Physiology of Behavior 11th Edition by Carlson

Chapter 4: Psychopharmacology

Topic	Question Type	Factual	Conceptual	Application
Introduction	Multiple Choice	1,3	2,4
	Fill-In
	Essay	1,2
Principles of Psychopharmacology	Multiple Choice	5,18,25,30,31,34
	Fill-In
	Essay	3,4
Sites of Drug Action	Multiple Choice	40,42,44,46,48,51,53	43,47,49,50,54	41,45-52
	Fill-In	11,12,13
	Essay	5
Neurotransmitters and Neuromodulators	Multiple Choice	56,61-63,68,72,75-77,81,86,88,89,96,104,106,108	55,57-60,64,66,67,69, 70-74,78,79,82-85,90-94,98,101,103,105,107,109,110	99,100,102
	Fill-In	14-20
	Essay	7,8,10	9	6

Multiple-Choice Questions

4.1-1.  Ingestion of  ________ can result in fatal paralysis of the muscles.

a. fluoxetine

b. botulinum toxin

c. amphetamine

d. L-DOPA.

e. atropine

Difficulty: 1

Question ID: 4.1-1

Page Ref: 100  

Topic: Opening 

Vignette Skill: Factual

Answer: b. botulinum toxin

Rationale: Ingestion of botulinum toxin can result in fatal paralysis of the muscles. 

4.1-2.  A key characteristic of a drug, as defined in the text, is that it

a. must be an endogenous chemical.

b. can include essential nutrients.

c. is effective only at high doses.

d. can be abused or misused by humans. 

e. is an exogenous chemical.

Difficulty: 2

Question ID: 4.1-2

Page Ref: 100    

Topic: Introduction

Skill: Conceptual

Answer: e. is an exogenous chemical.

Rationale: A drug is defined by the text as an exogenous chemical. 

4.1-3. ________  refers to the study of the effects of drugs on the nervous system and behavior.

a. Pseudopharmacology

b. Neuropharmacology

c. Psychoimmunology

d. Neurochemistry 

e. Psychopharmacology

 Difficulty: 1

Question ID: 4.1-3

Page Ref: 100   

Topic: Introduction

Skill: Factual

Answer: e. Psychopharmacology

Rationale:  Psychopharmacology involves the study of the effects of drugs on the nervous system and behavior.

4.1-4. ________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

a. Pharmacotherapy

b. Pharmacokinetics 

c. Drug metabolism 

d. Pharmacodynamics 

e. Neurobotany

Difficulty: 1

Question ID: 4.1-4

Page Ref: 101  

Topic: Pharmacokinetics

 Skill: Conceptual 

Answer: b. Pharmacokinetics

Rationale: Pharmacokinetics refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

4.1-5.  Dr. Jackson is doing research in which she examines whether a drug effect is different depending on whether the drug is given orally or rectally. We might say that she is doing a study involving

a. neurotherapy.

b. neurochemistry.

c. behavioral neuroscience.

d. pharmacokinetics.

e. neuropharmacology.

Difficulty: 1

Question ID: 4.1-5

Page Ref: 101  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: d. pharmacokinetics.

Rationale: Dr. Jackson is conducting a pharmacokinetic study that compares different routes of administration.

4.1-6.  The ________ route is the fastest way for a drug to reach the brain.

a. oral

b. topical

c. intravenous

d. intramuscular

e. intraperitoneal 

Difficulty: 1

Question ID: 4.1-6

Page Ref: 101   

Topic: Pharmacokinetics

Skill: Factual

Answer: c. intravenous

Rationale: The intravenous route is the fastest way for a drug to reach the brain.

4.1-7.  An important drawback to the ________ route is the high likelihood of accidental overdose.

a. oral

b. topical

c. intravenous

d. intramuscular 

e. intraperitoneal

Difficulty: 1

Question ID: 4.1-7

Page Ref: 101  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: c. intravenous

Rationale: The intravenous route can result in an accidental overdose.

 

4.1-8.  The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

a. intraperitoneal

b. oral

c. intravascular 

d. topical

e. intranasal

Difficulty: 1

Question ID: 4.1-8

Page Ref: 101  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: a. intraperitoneal

Rationale: Drugs are commonly given to rats via the intraperitoneal route.

4.1-9.  The ________ route of drug administration is most commonly used for humans.

a. intraperitoneal 

b. oral

c. intravascular 

d. topical

e. intranasal

Difficulty: 1

Question ID: 4.1-9

Page Ref: 102  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: b. oral

Rationale: Humans commonly take drugs via the oral route. 

4.1-10.  James snorts a small amount of cocaine into his nose using a rolled up dollar bill. The formal term for this route of cocaine administration would be

a. inhalation.

b. insufflation. 

c. intravenous 

d. intrarectal.

e. sublingual.

Difficulty: 2

Question ID:  4.1-10

Page Ref:  102  

Topic: Pharmacokinetics

Skill:  Applied

Answer: b. insufflation.

Rationale: Insufflation is the formal name for nasal snorting of a drug.

4.1-11.  A drug that might cause stomach upset if taken orally can alternatively be administered to a human via

a. injection into the gut.

b. the sublingual route.

c. a topical patch.

d. the intracranial route. 

e. a rectal suppository.

Difficulty:  1

Question ID: 4.1-11

Page Ref:  102   

Topic: Pharmacokinetics

Skill: Conceptual

Answer: e. a rectal suppository.

Rationale: A rectal suppository can deliver a drug into the blood without stomach upset .

4.1-12.  Neil has accidentally ingested a toxic chemical, which has made him unconscious and will soon kill him. Which route of administration would emergency physicians most likely use to administer an antidote for the toxin?

a. intravenous

b. oral

c. topical 

d. rectal

e. nasal  

Difficulty: 2

Question ID: 4.1-12

Page Ref:  101   

Topic: Pharmacokinetics

Skill: Applied

Answer: a. intravenous

Rationale: The intravenous route rapidly delivers antidotes into the body and can be used for an unconscious person. 

4.1-13.  The ________ route of drug administration has the advantage of bypassing the blood-brain barrier.

a. intraperitoneal

b. oral

c. intravascular

d. topical

e. intracerebroventricular

Difficulty: 1

Question ID: 4.1-13

Page Ref: 102  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: e. intracerebroventricular

Rationale:  Drugs administered via the intracerebroventricular route bypass the blood-brain barrier. 

4.1-14.  An increase in ________ for a drug would cause that drug to more rapidly reach the brain.

a. metabolism of the drug via the liver

b. lipid solubility

c. water solubility

d. depot binding of the drug in blood, bone and fat

e. kidney excretion

Difficulty: 1

Question ID: 4.1-14

Page Ref: 103  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: b. lipid solubility 

Rationale: An increase in lipid solubility for a drug would cause that drug to more rapidly reach the brain.

4.1-15.  Which of the following is true of drug effects?

a. Drugs vary widely in their effectiveness.

b. Drugs continue to show increases of effect even with super-large doses.

c. Heavier animals usually require lower drug doses than do lighter animals. 

d. A drug has only one effect.

e. For a given animal weight, twice as much drug always has twice the effect.

Difficulty: 1

Question ID: 4.1-15    

Page Ref: 103   

Topic: Drug Effectiveness

Skill: Conceptual

Answer: a. Drugs vary widely in their effectiveness.

Rationale: Drugs vary widely in their effectiveness.

4.1-16.  The primary route of excretion of drugs from the body is via the

a. liver.

b. lung.

c. mucosa. 

d. kidneys. 

e. skin.

Difficulty: 1

Question ID: 4.1-16   

Page Ref: 103  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: d. kidneys.

Rationale: The primary route of excretion of drugs from the body is via the kidneys.

4.1-17.  The primary organ that metabolizes drugs is the 

a. liver. 

b. lung.

c. mucosa. 

d. kidneys. 

e. skin.

Difficulty: 1

Question ID: 4.1-17

Page Ref: 103  

Topic: Pharmacokinetics

Skill: Conceptual

Answer: a.  liver.  

Rationale: The primary organ that metabolizes drugs is the liver.